SUN TEN is a leading manufacturer of Chinese herbal extract products, including the famous SUN TEN brand of Chinese herbal formula products and single herbal medicines. As a manufacturer, SUN TEN also functions as full service OEM/private contract manufacturer specializing in Chinese herb extract products. SUN TEN also has the experience, resources and scientific infrastructure to manufacture products that meet the detailed specifications necessary for scientific studies.
Historically the majority of classical Chinese herbal formulas have been decocted by water. It offers excellent medicinal constituent extraction as a neutral solvent that doesn’t alter the desired medicinal actions of the herbs. The water-based decoction process draws out the desired medicinal constituents and optimizes the formula’s unique character. All the ingredients of a formula decoct together in water yields a product that is synergistically refined and more potent than the sum of ingredients if taken individually. SUN TEN uses only water-based decoction methods for the entire manufacturing process. This includes essential oil recovery.
The sequence of herbs input within a decoction determines the efficacy of a formula. For example, the rhubarb (Da Huang) in Rhubarb & Mirabilitum Combination (Tiao Wei Cheng Qi Tang) must be decocted first, followed by other ingredients to enable the formula to offer the therapeutic effect “harmonize the stomach and soothe the qi. On the other hand, the rhubarb in Major Rhubarb Combination (Da Cheng Qi Tang) must be decocted last which enables the formula to offer the effect “purge down the evils quickly”. Comprehensive chemistries will change upon the sequence of herbal decoction. SUN TEN follows an established sequence of decoction appropriate to each formulation due to the desired efficacy of the final product depends on it.
Essential Oil Recovery
According to traditional Chinese herbal preparation methodologies, handling certain herbal medicines are paramount to ensure efficacy. When preparing aromatic herbal medicines by decoction, it is known that they must be added during the last few minutes of the decoction process. This is because prolonged exposure to intense heat will damage and evaporate the essential oils which contain active constituents needed to deliver the desired medicinal effect.
When manufacturing at a large scale using pharmaceutical grade closed-decoction procedures, handling herbal medicines that contain sensitive essential oils need an alternative and scientific procedure to retain essential oil. An estimated 23%-29% of the active volatile components are typically lost during the manufacture process. It was discovered by analyzing the constituents retained from recollected distillate that majority of active constituents were lost. In order to prevent the loss of thermal sensitive constituents, a proprietary essential oil recovery device has been developed to retain the active ingredients and maximize the efficacy of the finished product. The active constituents of essential oil retained are validated by analytical verification.
Low temperature vacuum concentration can prevent substantial loss of thermal sensitive constituents.
Fluid bed granulation, the final step of processing by transforming concentrated liquid to granules, is conducted with the addition of an excipient to stabilize the finished product.
The use of excipients in Chinese herbal extracts is necessary to transform concentrated herbal extract liquid into dry granule. The amount of excipients used in each product varies depending on the characteristics of the herbs within the formulation. Without the correct amount of excipient, the granules will absorb atmospheric moisture once it’s exposed to air which inevitably clump together and become unstable. SUN TEN uses GMO free corn starch as an excipient. SUN TEN never use genetically modified corn starch.